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HPA-Global News

October 27, 2025

HPA (China) News – October 2025

A leading gut microbiome brand under Novo Nordisk Denmark, Microbiome Labs, has officially established a strategic partnership with Zhongjian Lianxing, a high-end nutrition and health supply chain enterprise in China. Both parties will leverage Zhongjian Lianxing’s extensive resources and professional capabilities in the medical channel to jointly advance the strategic layout and innovative service model for Microbiome Labs’ professional probiotic products in China’s medical and pharmaceutical market. This cooperation represents not only an expansion of distribution channels but also a deep integration of brand value and professional resources.
DSM-Firmenich has launched a new generation of Dairy Safe™ fermentation cultures, suitable for semi-hard, hard, and European-style cheeses.
According to the company, the culture series improves resistance to bacteriophages and thermal stability while ensuring consistent acidification, uniform eye formation, and faster flavor development in cheese. Dairy Safe™ combines nisin-producing and nisin-insensitive strains, with a nisin content higher than that of comparable products on the market, effectively inhibiting spoilage bacteria. The product provides two flavor profiles — creamy savory and light broth sweetness — and is suitable for cow, goat, and sheep milk.
The Indonesian Food and Drug Authority (BPOM) has officially issued Regulation No. 17 of 2025 on the Guidelines for the Evaluation of Health Supplements Containing Probiotics (PerBPOM 17/2025). This regulation repeals BPOM Regulation No. 17 of 2021 on the same subject. It aims to provide clearer technical guidance for both companies and BPOM evaluators when assessing probiotic health supplements prior to granting market authorization.
On September 15, Fenghua Biotech announced that its core probiotic strain, CP-9 (Bifidobacterium animalis subsp. lactis), has officially received “Generally Recognized as Safe” (GRAS) certification from the U.S. FDA. The strain is now approved for use in 11 categories of foods and beverages, including sports drinks, dairy products, and infant foods, at a maximum level of 10⁹ CFU per serving. Following the 2023 GRAS certification of strain MP108, this marks another FDA approval for Fenghua, making it one of the few probiotic ingredient manufacturers in Taiwan with multiple GRAS-certified strains.
Lallemand has announced the introduction of a series of advanced instruments for its Expert’Biome CDMO division. The new equipment includes high-end analytical tools such as Q-PCR and MALDI-TOF, which enable the production of active pharmaceutical ingredients and finished drugs under anaerobic conditions. This enhancement further strengthens Lallemand’s GMP pharmaceutical manufacturing capabilities for next-generation strains.
On September 25, according to the European Food Safety Authority (EFSA), the Panel on Nutrition, Novel Foods and Food Allergens (NDA) published a scientific opinion on the safety of extending the use of pasteurised Akkermansia muciniphila as a novel food. The panel concluded that for adolescents aged 12 to 14 years, pasteurised Akkermansia muciniphila is safe at doses up to 2.1×10¹⁰ cells per day, and for adolescents aged 14 to 18 years, it is safe at doses up to 3.0×10¹⁰ cells per day. The safety of this ingredient has not yet been established for pregnant or lactating women.
Kongduoka has launched a new dietary fiber beverage called “Super Fruit & Vegetable Drink Light Strip.” According to the company, the product is made from extracts of 15 super fruits and vegetables, including kale and broccoli, and contains dual dietary fibers and 15 billion probiotics, as well as six types of vitamins and minerals. Its fiber content is equivalent to the amount found in approximately 875 grams of tomatoes. The probiotic strains added include Bifidobacterium animalis CECT8145 (BPL1®), Bifidobacterium animalis subsp. lactis HN01, Lactiplantibacillus plantarum LP-KFY04, and four other strains, making it suitable for various scenarios such as work and fitness.
Herun has launched a new 0-sucrose, 0-lactose, high-dietary-fiber fermented milk product. According to the company, this fermented milk adopts a scientific formula and is specially fortified with multiple probiotic strains, including Bifidobacterium animalis subsp. lactis, Lactobacillus delbrueckii subsp. bulgaricus, and Streptococcus thermophilus. It also incorporates whey powder and whey protein powder for rich and balanced nutrition. Each 100 grams of the product contains 4 grams of protein and at least 3.8 grams of naturally synthesized dietary fiber—equivalent to the fiber content of three bananas—helping effectively promote intestinal health.
Asahi has launched a new “Immune Support Yogurt Sour-Flavored Non-Alcoholic Beverage” under its Style Balance brand.
According to the company, the product is categorized as a “Foods with Functional Claims” product in Japan and contains Lactobacillus acidophilus strain L-92, which has been reported to help maintain immune function in healthy individuals.
In addition, the beverage contains no alcohol, sugar, or calories.
Asahi Calpis has launched the first concentrated beverage in its “PLUS Calpis” series.According to the brand, the new product line falls under Japan’s “Foods with Functional Claims” category and includes two variants — “Sleep & Gut Care” and “Immune Support.” “Sleep & Gut Care” contains Lactobacillus gasseri CP2305, which has been shown in studies to help alleviate psychological stress, improve sleep quality, and enhance gut health. “Immune Support” contains Lactobacillus acidophilus L-92, which is reported to help maintain immune function and relieve nasal discomfort caused by dust or pollen. The product can be diluted to make approximately nine servings of beverages and contains about 60% fewer calories than regular Calpis, suitable for mixing with water or soda water.
Yanyanyansheng has announced the launch of its new high-activity probiotic product, Peiruoguan 100, which contains 60 billion live bacteria per sachet.
Based on a triple synergy formula of probiotics, prebiotics, and postbiotics, it builds a comprehensive “beneficial–nourishing–balancing” microbial ecosystem to enhance probiotic survival in the gut.
Furthermore, Peiruoguan 100 achieves a high addition level of 60 billion live bacteria per sachet, ensuring an adequate amount of active bacterial colonies successfully reach the intestines to strengthen the gut microbiome defense barrier.
Lifeway Foods has launched a new functional beverage. According to the company, the new drink contains 20 grams of protein, 5 grams of creatine, and 12 types of active probiotics in a lactose-free formula. It is designed to cater to a wide range of consumers — from professional athletes and fitness enthusiasts to general health-conscious individuals — and is suitable for work, study, or exercise occasions.
On September 12, the research team led by Academician Lu Lin from Peking University Sixth Hospital presented a report titled “Gut–Brain Axis Mechanisms and Intervention Strategies for Child and Adolescent Psychiatric Disorders.”
The report pointed out that as a bidirectional regulatory network connecting the gastrointestinal tract and the nervous system, the gut–brain axis plays a significant role in mental disorders. On one hand, gut microbiota interventions can improve depressive disorders, bipolar affective disorder, and cognitive impairment caused by sleep deprivation. On the other hand, abnormal gut microbiota in infancy may increase the risk of neurodevelopmental disorders and affect the development of the nervous system in children.
Morinaga Milk Industry Co., Ltd. in Japan has launched a new postbiotic ingredient called LAC-Living+, which focuses on improving mood and maintaining a positive emotional state, bringing new vitality to the field of emotional wellness.
According to the company, LAC-Living+ is derived from Morinaga’s proprietary lactic acid bacterial strain Lactobacillus helveticus MCC1848, which undergoes heat inactivation during production.
This process preserves its active components while providing a longer shelf life and broader application flexibility. Its core mechanism supports emotional health through modulation of the gut–brain axis. Clinical research has further validated its efficacy and safety. A randomized controlled trial involving 58 participants showed that four weeks of continuous supplementation with LAC-Living+ significantly improved feelings of “friendliness” and “relaxation.” Another study involving 46 nursing students also demonstrated a significant increase in their “positive affect” scores. No adverse effects were reported in either trial, indicating good safety. Thanks to its excellent heat resistance and stability, LAC-Living+ can be widely applied in various product forms, including beverages, snacks, baked goods, and dietary supplements. Building on its success in the Japanese market, Morinaga Milk plans to further expand this innovative ingredient to the Asia-Pacific region and global markets.
JENYAO Health stated on its investor interaction platform that the company is focusing on probiotic technology and innovation in health foods.
Its subsidiary, JENYAO Runying, has independently developed an inactivated bacterial strain, AKKBG-001™, which successfully solves the industry challenge of probiotic stability in liquid carriers. Whole-genome sequencing has confirmed that the strain possesses good safety and intestinal regulatory functions. This strain has already been applied to various end products such as probiotic dairy beverages and “yogurt companion” formulations, promoting innovative integration and health-oriented application of probiotics in dairy products.